Overview

A Brain Imaging Study With Positron Emission Tomography and the Radiotracer [11C]UCB-J to Estimate How Fast Brivaracetam and Levetiracetam Enter the Brain in Healthy Volunteers

Status:
Completed

Trial end date:
2017-09-01

Target enrollment:

Participant gender:

Summary

This study will estimate how fast two antiepileptic drugs (Levetiracetam and Brivaracetam) enter the human brain. Brain imaging will be used to measure how quickly the radioactive probe [11C]UCB-J exits the brain when Levetiracetam or Brivaracetam are given. This will be used to estimate how fast the antiepileptic drugs enter the brain.

Phase:

Phase 1

Details

Lead Sponsor:

UCB Biopharma S.P.R.L.
UCB Pharma

Collaborators:

PRA Health Sciences
Yale University

Treatments:

Brivaracetam
Etiracetam
Levetiracetam
Piracetam